MYO5B antibody (N-Term)

Catalog No. ABIN966630

Product Details anti-MYO5B Antibody

Target: MYO5B (Myosin VB (MYO5B))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYO5B antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human Myosin-5B (Myosin Vb)

Application Details

Restrictions: For Research Use only

Handling

Buffer: This antibody is stored in PBS, 0.01% sodium azide and 50% glycerol.

Storage: -20 °C

References for anti-MYO5B antibody (ABIN966630)

Szperl, Golachowska, Bruinenberg, Prekeris, Thunnissen, Karrenbeld, Dijkstra, Hoekstra, Mercer, Ksiazyk, Wijmenga, Wapenaar, Rings, van IJzendoorn: "Functional characterization of mutations in the myosin Vb gene associated with microvillus inclusion disease." in: Journal of pediatric gastroenterology and nutrition, Vol. 52, Issue 3, pp. 307-13, (2011) (PubMed).

Target Details for MYO5B

Target: MYO5B (Myosin VB (MYO5B))

Alternative Name: MYO5B (MYO5B Products)

Synonyms: AI661750 antibody, mKIAA1119 antibody, Myr6 antibody, myosin VB antibody, myosin Vb antibody, MYO5B antibody, Myo5b antibody

Background: MYO5B(Myosin-5B)(Myosin Vb)interacts with RAB11FIP2. MYO5B(Myosin-5B)(Myosin Vb) has a role in in glutamate receptor GluR1 trafficking. The myosin Vb functions in traffic between peripheral and pericentrosomal compartments. The protein contains 1 dilute domain and 6 IQ domains. It also contains 1 myosin head-like domain. The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament