VANGL2 antibody (AA 1-110)

Catalog No. ABIN7175358

The Rabbit Polyclonal anti-VANGL2 antibody has been validated for WB, ELISA and IHC. It is suitable to detect VANGL2 in samples from Human.

Quick Overview for VANGL2 antibody (AA 1-110) (ABIN7175358)

Target: VANGL2 (Vang-Like 2 (VANGL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VANGL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-VANGL2 Antibody

Binding Specificity: AA 1-110

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Vang-like protein 2 protein (1-110AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for VANGL2

Target: VANGL2 (Vang-Like 2 (VANGL2))

Alternative Name: VANGL2

Background:

Background: Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity).

Aliases: Homolog of Drosophila strabismus antibody, KIAA1215 antibody, Loop tail associated protein antibody, loop tail protein 1 homolog antibody, Loop-tail protein 1 homolog antibody, LPP 1 antibody, LPP1 antibody, LTAP antibody, MGC119403 antibody, MGC119404 antibody, STB 1 antibody, STB1 antibody, STBM 1 antibody, STBM antibody, STBM1 antibody, Strabismus 1 antibody, van Gogh like protein 2 antibody, Van Gogh-like protein 2 antibody, Vang (van gogh, Drosophila) like 2 antibody, Vang like 2 (van gogh, Drosophila) antibody, vang like 2 antibody, vang like protein 2 antibody, Vang-like protein 2 antibody, VANG2_HUMAN antibody, VANGL 2 antibody, VANGL planar cell polarity protein 2 antibody, Vangl2 antibody

UniProt: Q9ULK5

Pathways: WNT Signaling, Stem Cell Maintenance, Tube Formation, Asymmetric Protein Localization