VEGFA antibody (AA 27-191) (Biotin)

Catalog No. ABIN7175365

This anti-VEGFA antibody is a Rabbit Polyclonal antibody detecting VEGFA in ELISA. Suitable for Human.

Quick Overview for VEGFA antibody (AA 27-191) (Biotin) (ABIN7175365)

Target: VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VEGFA antibody is conjugated to Biotin

Application: ELISA

Product Details anti-VEGFA Antibody (Biotin)

Binding Specificity: AA 27-191

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Vascular endothelial growth factor A protein (27-191AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for VEGFA

Target: VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

Alternative Name: VEGFA

Background:

Background: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.

Aliases: glioma-derived endothelial cell mitogen antibody, MGC70609 antibody, MVCD1 antibody, Vascular endothelial growth factor A antibody, Vascular Endothelial Growth Factor antibody, Vascular permeability factor antibody, VEGF antibody, VEGF-A antibody, VEGF165 antibody, Vegfa antibody, VEGFA_HUMAN antibody, VPF antibody

UniProt: P15692

Pathways: RTK Signaling, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling