LRRC8E antibody (AA 353-630)

Catalog No. ABIN7175622

The Rabbit Polyclonal anti-LRRC8E antibody is suitable to detect LRRC8E in samples from Human. It has been validated for ELISA, IHC and IF.

Quick Overview for LRRC8E antibody (AA 353-630) (ABIN7175622)

Target: LRRC8E (Leucine Rich Repeat Containing 8 Family, Member E (LRRC8E))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC8E antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-LRRC8E Antibody

Binding Specificity: AA 353-630

Purpose: LRRC8E Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Volume-regulated anion channel subunit LRRC8E protein (353-630AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LRRC8E

Target: LRRC8E (Leucine Rich Repeat Containing 8 Family, Member E (LRRC8E))

Alternative Name: LRRC8E

Background:

Background: Component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8E constitutes a pore-forming subunit or whether it is closely associated with the pore (By similarity).

Aliases: LRRC8E antibody, Volume-regulated anion channel subunit LRRC8E antibody, Leucine-rich repeat-containing protein 8E antibody

UniProt: Q6NSJ5