LRRC8E antibody (AA 353-630) (FITC)

Catalog No. ABIN7175624

Product Details anti-LRRC8E Antibody (FITC)

Target: LRRC8E (Leucine Rich Repeat Containing 8 Family, Member E (LRRC8E))

Binding Specificity: AA 353-630

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC8E antibody is conjugated to FITC

Application: Please inquire

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Volume-regulated anion channel subunit LRRC8E protein (353-630AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LRRC8E

Target: LRRC8E (Leucine Rich Repeat Containing 8 Family, Member E (LRRC8E))

Alternative Name: LRRC8E (LRRC8E Products)

Synonyms: 1810049O03Rik antibody, C87354 antibody, RGD1311979 antibody, leucine rich repeat containing 8 VRAC subunit E L homeolog antibody, leucine rich repeat containing 8 VRAC subunit E antibody, leucine rich repeat containing 8 family, member E antibody, lrrc8e.L antibody, LRRC8E antibody, Lrrc8e antibody

Background:

Background: Component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8E constitutes a pore-forming subunit or whether it is closely associated with the pore (By similarity).

Aliases: LRRC8E antibody, Volume-regulated anion channel subunit LRRC8E antibody, Leucine-rich repeat-containing protein 8E antibody

UniProt: Q6NSJ5