WAPAL antibody (AA 1037-1190)

Catalog No. ABIN7175822

Product Details anti-WAPAL Antibody

Target: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Binding Specificity: AA 1037-1190

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WAPAL antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Wings apart-like protein homolog protein (1037-1190AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for WAPAL

Target: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Alternative Name: WAPL (WAPAL Products)

Synonyms: RGD1308960 antibody, FOE antibody, KIAA0261 antibody, WAPL antibody, 2410073G16 antibody, A530089A20Rik antibody, BC037674 antibody, mKIAA0261 antibody, mWAPL antibody, WAPL cohesin release factor antibody, Wapl antibody, WAPL antibody, wapl antibody

Background:

Background: Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.

Aliases: FOE antibody, Friend of EBNA2 (Epstein Barr virus nuclear protein 2) antibody, Friend of EBNA2 protein antibody, KIAA0261 antibody, OTTHUMP00000020004 antibody, WAPAL antibody, WAPL antibody, WAPL_HUMAN antibody, Wings apart like homolog antibody, Wings apart like homolog (Drosophila) antibody, Wings apart-like protein homolog antibody

UniProt: Q7Z5K2

Pathways: Chromatin Binding