WAC antibody (AA 10-102) (Biotin)

Catalog No. ABIN7175868

Product Details anti-WAC Antibody (Biotin)

Target: WAC (WW Domain Containing Adaptor with Coiled-Coil (WAC))

Binding Specificity: AA 10-102

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WAC antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human WW domain-containing adapter protein with coiled-coil protein (10-102AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for WAC

Target: WAC (WW Domain Containing Adaptor with Coiled-Coil (WAC))

Alternative Name: WAC (WAC Products)

Synonyms: BM-016 antibody, PRO1741 antibody, Wwp4 antibody, 1110067P07Rik antibody, A230035H12Rik antibody, AI256735 antibody, AI256776 antibody, DKFZp468H162 antibody, wac antibody, wu:fc13f04 antibody, wu:fj68f01 antibody, zgc:55755 antibody, RGD1562407 antibody, zgc:101828 antibody, WW domain containing adaptor with coiled-coil antibody, WW domain containing adaptor with coiled-coil a antibody, WW domain containing adaptor with coiled-coil b antibody, WAC antibody, Wac antibody, wac antibody, waca antibody, wacb antibody

Background:

Background: Acts as a linker between gene transcription and histone H2B monoubiquitination at \\\'Lys-120\\\' (H2BK120ub1). Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription. Regulates the cell-cycle checkpoint activation in response to DNA damage. Positive regulator of amino acid starvation-induced autophagy. May negatively regulate the ubiquitin proteasome pathway.

Aliases: 1110067P07Rik antibody, BA48B24 antibody, BA48B24.1 antibody, BM 016 antibody, FLJ31290 antibody, KIAA1844 antibody, MGC10753 antibody, OTTHUMP00000019380 antibody, OTTHUMP00000019382 antibody, PRO1741 antibody, wac antibody, WAC_HUMAN antibody, WW domain containing adapter protein with coiled coil antibody, WW domain containing adaptor with coiled coil antibody, WW domain-containing adapter protein with coiled-coil antibody, Wwp4 antibody

UniProt: Q9BTA9

Pathways: Chromatin Binding