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Survivin antibody (AA 1-140) (Biotin)

This Rabbit Polyclonal antibody specifically detects Survivin in ELISA. It exhibits reactivity toward Mouse.
Catalog No. ABIN7176986

Quick Overview for Survivin antibody (AA 1-140) (Biotin) (ABIN7176986)

Target

See all Survivin (BIRC5) Antibodies
Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reactivity

  • 131
  • 57
  • 48
  • 1
  • 1
  • 1
  • 1
  • 1
Mouse

Host

  • 98
  • 42
  • 1
  • 1
Rabbit

Clonality

  • 93
  • 49
Polyclonal

Conjugate

  • 82
  • 12
  • 11
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Survivin antibody is conjugated to Biotin

Application

  • 111
  • 56
  • 45
  • 42
  • 26
  • 26
  • 24
  • 20
  • 14
  • 13
  • 7
  • 6
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
ELISA
  • Binding Specificity

    • 21
    • 16
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-140

    Cross-Reactivity

    Mouse

    Purification

    >95%, Protein G purified

    Immunogen

    Recombinant Mouse Baculoviral IAP repeat-containing protein 5 protein (1-140AA)

    Isotype

    IgG
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

    Alternative Name

    Birc5

    Background

    Background: Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex, directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May counteract a default induction of apoptosis in G2/M phase. The acetylated form represses STAT3 transactivation of target gene promoters. May play a role in neoplasia. Inhibitor of CASP3 and CASP7.

    Aliases: Birc5 antibody, Api4 antibody, Iap4Baculoviral IAP repeat-containing protein 5 antibody, Apoptosis inhibitor 4 antibody, Apoptosis inhibitor survivin antibody, TIAP antibody

    UniProt

    O70201

    Pathways

    Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
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