CD74 antibody (AA 56-279) (Biotin)

Catalog No. ABIN7177274

This Rabbit Polyclonal antibody specifically detects CD74 in ELISA. It exhibits reactivity toward Mouse.

Quick Overview for CD74 antibody (AA 56-279) (Biotin) (ABIN7177274)

Target: CD74 (HLA-DR-gamma (CD74))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD74 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-CD74 Antibody (Biotin)

Binding Specificity: AA 56-279

Cross-Reactivity: Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Mouse H-2 class II histocompatibility antigen gamma chain protein (56-279AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CD74

Target: CD74 (HLA-DR-gamma (CD74))

Alternative Name: Cd74

Background:

Background: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.

Aliases: Cd74 antibody, Ii antibody, H-2 class II histocompatibility antigen gamma chain antibody, Ia antigen-associated invariant chain antibody, Ii antibody, MHC class II-associated invariant chain antibody, CD antigen CD74) [Cleaved into: Class-II-associated invariant chain peptide antibody, CLIP)] antibody

UniProt: P04441

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints