Nkx2-2 antibody (AA 1-273) (Biotin)

Catalog No. ABIN7177298

This Rabbit Polyclonal antibody specifically detects Nkx2-2 in ELISA. It exhibits reactivity toward Mouse.

Quick Overview for Nkx2-2 antibody (AA 1-273) (Biotin) (ABIN7177298)

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nkx2-2 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-Nkx2-2 Antibody (Biotin)

Binding Specificity: AA 1-273

Cross-Reactivity: Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Mouse Homeobox protein Nkx-2.2 protein (1-273AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Nkx2-2

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Alternative Name: Nkx2-2

Background:

Background: Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter.

Aliases: Nkx2-2 antibody, Nkx-2.2 antibody, Nkx2b antibody, Homeobox protein Nkx-2.2 antibody, Homeobox protein NK-2 homolog B antibody

UniProt: P42586

Pathways: Dopaminergic Neurogenesis