Murinoglobulin 1 antibody (AA 700-910)

Catalog No. ABIN7177702

Product Details anti-Murinoglobulin 1 Antibody

Target: Murinoglobulin 1 (Mug1)

Binding Specificity: AA 700-910

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Murinoglobulin 1 antibody is un-conjugated

Application: ELISA

Cross-Reactivity: Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Mouse Murinoglobulin-1 protein (700-910AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Murinoglobulin 1

Target: Murinoglobulin 1 (Mug1)

Alternative Name: Mug1 (Mug1 Products)

Synonyms: murinoglobulin 1 antibody, Mug1 antibody

Background:

Background: A proteinase activates the inhibitor by specific proteolysis in the bait region, which, by an unknown mechanism leads to reaction at the cysteinyl-glutamyl internal thiol ester site and to a conformational change, whereby the proteinase is trapped and/or covalently bound to the inhibitor. While in the tetrameric proteinase inhibitors steric inhibition is sufficiently strong, monomeric forms need a covalent linkage between the activated glutamyl residue of the original thiol ester and a terminal amino group of a lysine or another nucleophilic group on the proteinase, for inhibition to be effective.lysine or another nucleophilic group on the proteinase, for inhibition to be effective.

Aliases: Mug1 antibody, Mug-1Murinoglobulin-1 antibody, MuG1 antibody

UniProt: P28665