PDGFD antibody (AA 24-370) (HRP)

Catalog No. ABIN7177757

This Rabbit Polyclonal antibody specifically detects PDGFD in ELISA. It exhibits reactivity toward Mouse.

Quick Overview for PDGFD antibody (AA 24-370) (HRP) (ABIN7177757)

Target: PDGFD (Platelet Derived Growth Factor D (PDGFD))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFD antibody is conjugated to HRP

Application: ELISA

Product Details anti-PDGFD Antibody (HRP)

Binding Specificity: AA 24-370

Cross-Reactivity: Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Mouse Platelet-derived growth factor D protein (24-370AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PDGFD

Target: PDGFD (Platelet Derived Growth Factor D (PDGFD))

Alternative Name: Pdgfd

Background:

Background: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing (By similarity). Has oncogenic potential and can induce tumor formation. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix.

Aliases: Pdgfd antibody, Scdgfb antibody, Platelet-derived growth factor D antibody, PDGF-D antibody, Spinal cord-derived growth factor B antibody, SCDGF-B) [Cleaved into: Platelet-derived growth factor D antibody, latent form antibody, PDGFD latent form), Platelet-derived growth factor D antibody, receptor-binding form antibody, PDGFD receptor-binding form)] antibody

UniProt: Q925I7

Pathways: RTK Signaling, Platelet-derived growth Factor Receptor Signaling