CD163 antibody (AA 86-365) (Biotin)
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- Target See all CD163 Antibodies
- CD163
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Binding Specificity
- AA 86-365
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CD163 antibody is conjugated to Biotin
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Application
- ELISA
- Cross-Reactivity
- Mouse
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Mouse Scavenger receptor cysteine-rich type 1 protein M130 protein (86-365AA)
- Isotype
- IgG
- Top Product
- Discover our top product CD163 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CD163
- Alternative Name
- Cd163 (CD163 Products)
- Synonyms
- DMBT1 antibody, CD163 antibody, CD163v2 antibody, CD163v3 antibody, M130 antibody, MM130 antibody, deleted in malignant brain tumors 1 protein-like antibody, CD163 molecule antibody, CD163 antigen antibody, LOC426820 antibody, CD163 antibody, Cd163 antibody
- Background
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Background: Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 (By similarity).
Aliases: Cd163 antibody, M130Scavenger receptor cysteine-rich type 1 protein M130 antibody, CD antigen CD163) [Cleaved into: Soluble CD163 antibody, sCD163)] antibody
- UniProt
- Q2VLH6
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