Calreticulin antibody (AA 18-417)

Catalog No. ABIN7178241

The Rabbit Polyclonal anti-Calreticulin antibody has been validated for ELISA. It is suitable to detect Calreticulin in samples from Pig.

Quick Overview for Calreticulin antibody (AA 18-417) (ABIN7178241)

Target: Calreticulin (CALR)

Reactivity: Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calreticulin antibody is un-conjugated

Application: ELISA

Product Details anti-Calreticulin Antibody

Binding Specificity: AA 18-417

Cross-Reactivity: Pig

Purification: >95%, Protein G purified

Immunogen: Recombinant Pig Calreticulin protein (18-417AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Calreticulin

Target: Calreticulin (CALR)

Alternative Name: CALR

Background:

Background: Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis.

Aliases: CALRCalreticulin antibody, CRP55 antibody, Calregulin antibody, Endoplasmic reticulum resident protein 60 antibody, ERp60 antibody, HACBP antibody

UniProt: P28491

Pathways: Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response