F12 antibody (AA 20-371) (Biotin)

Catalog No. ABIN7178246

This Rabbit Polyclonal antibody specifically detects F12 in ELISA. It exhibits reactivity toward Pig.

Quick Overview for F12 antibody (AA 20-371) (Biotin) (ABIN7178246)

Target: F12 (Coagulation Factor XII (F12))

Reactivity: Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F12 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-F12 Antibody (Biotin)

Binding Specificity: AA 20-371

Cross-Reactivity: Pig

Purification: >95%, Protein G purified

Immunogen: Recombinant Pig Coagulation factor XII protein (20-371AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for F12

Target: F12 (Coagulation Factor XII (F12))

Alternative Name: F12

Background:

Background: Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity).

Aliases: F12Coagulation factor XII antibody, EC 3.4.21.38 antibody, Hageman factor antibody, HAF) [Cleaved into: Coagulation factor XIIa heavy chain, Coagulation factor XIIa light chain] antibody

UniProt: O97507

Pathways: Complement System