F12 antibody (AA 20-371) (HRP)
Quick Overview for F12 antibody (AA 20-371) (HRP) (ABIN7178248)
Target
See all F12 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 20-371
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Cross-Reactivity
- Pig
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Pig Coagulation factor XII protein (20-371AA)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- F12 (Coagulation Factor XII (F12))
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Alternative Name
- F12
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Background
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Background: Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity).
Aliases: F12Coagulation factor XII antibody, EC 3.4.21.38 antibody, Hageman factor antibody, HAF) [Cleaved into: Coagulation factor XIIa heavy chain, Coagulation factor XIIa light chain] antibody
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UniProt
- O97507
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Pathways
- Complement System
Target
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