CD4 antibody (PE)

Catalog No. ABIN7178426

This Rat Monoclonal antibody specifically detects CD4 in FACS and ELISA. It exhibits reactivity toward Mouse.

Quick Overview for CD4 antibody (PE) (ABIN7178426)

Target: CD4

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD4 antibody is conjugated to PE

Application: Flow Cytometry (FACS), ELISA

Product Details anti-CD4 Antibody (PE)

Cross-Reactivity: Mouse

Purification: Affinity purified

Immunogen: Recombinant Protein

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09 % sodium azide and 0.2 % (w/v) BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CD4

Target: CD4

Alternative Name: CD4

Background:

Background: The 4AM15 monoclonal antibody reacts with the mouse CD4 Molecule, a 55 kDa cell surface receptor. It is a member of the lg superfamily,primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC classII and associating with the protein tyrosine kinase, lck.1. Nakamura.T. 1992.Personal communication.2. Bendelac.A.1995.Mouse NK1 T Cells.Curr.Opin.Immunol.7:367-3743. Shevach,E.M.2000.Regulatory T cells in autoimmunity.Annu.Rev.Immunol.

Aliases: N/A

UniProt: P01730

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events