GFER antibody (AA 1-198) (Biotin)

Catalog No. ABIN7178850

The Rabbit Polyclonal anti-GFER antibody has been validated for ELISA. It is suitable to detect GFER in samples from Rat.

Quick Overview for GFER antibody (AA 1-198) (Biotin) (ABIN7178850)

Target: GFER (Growth Factor, Augmenter of Liver Regeneration (GFER))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFER antibody is conjugated to Biotin

Application: ELISA

Product Details anti-GFER Antibody (Biotin)

Binding Specificity: AA 1-198

Cross-Reactivity: Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Rat FAD-linked sulfhydryl oxidase ALR protein (1-198AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GFER

Target: GFER (Growth Factor, Augmenter of Liver Regeneration (GFER))

Alternative Name: Gfer

Background:

Background: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. May have a function in liver regeneration and spermatogenesis.

Aliases: Gfer antibody, AlrFAD-linked sulfhydryl oxidase ALR antibody, EC 1.8.3.2 antibody, Augmenter of liver regeneration antibody

UniProt: Q63042

Pathways: SARS-CoV-2 Protein Interactome