NAMPT antibody (AA 231-491)

Catalog No. ABIN7178973

The Rabbit Polyclonal anti-NAMPT antibody has been validated for WB and ELISA. It is suitable to detect NAMPT in samples from Rat.

Quick Overview for NAMPT antibody (AA 231-491) (ABIN7178973)

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAMPT antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NAMPT Antibody

Binding Specificity: AA 231-491

Cross-Reactivity: Human, Rat

Purification: >95%, Antigen Affinity purified & Affinity purified

Immunogen: Recombinant Rat Nampt protein (231-491AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NAMPT

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Alternative Name: Nampt

Background:

Background: Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression.

Aliases: Nampt antibody, Pbef1 antibody, Nicotinamide phosphoribosyltransferase antibody, NAmPRTase antibody, Nampt antibody, EC 2.4.2.12 antibody, Pre-B-cell colony-enhancing factor 1 homolog antibody, PBEF antibody, Visfatin antibody

UniProt: Q80Z29