C-JUN antibody (Ser243)

Catalog No. ABIN7179983

This Rabbit Polyclonal antibody specifically detects C-JUN in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for C-JUN antibody (Ser243) (ABIN7179983)

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C-JUN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-C-JUN Antibody

Binding Specificity: Ser243

Cross-Reactivity: Human, Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human c-Jun around the phosphorylation site of serine 243.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for C-JUN

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Alternative Name: JUN

Background:

Background: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.

Boyle W J, et al. (1991) Cell. 64(3): 573-584.
Binetruy B, et al. (1991) Nature. 351: 122-127.
Smeal T, et al. (1991) Nature. 354:494-496.
Derijard B, et al. (1994) Cell. 76:1025-1037.
Kyriakis J M, et al. (1994) Nature. 369: 156-160.

Aliases: Activator protein 1 antibody, AP 1 antibody, AP-1 antibody, AP1 antibody, cJun antibody, Enhancer Binding Protein AP1 antibody, Jun Activation Domain Binding Protein antibody, JUN antibody, Jun oncogene antibody, JUN protein antibody, Jun proto oncogene antibody, JUN_HUMAN antibody, JUNC antibody, Oncogene JUN antibody, p39 antibody, Proto oncogene c jun antibody, Proto oncogene cJun antibody, Proto-oncogene c-jun antibody, Transcription Factor AP 1 antibody, Transcription factor AP-1 antibody, Transcription Factor AP1 antibody, V jun avian sarcoma virus 17 oncogene homolog antibody, V jun sarcoma virus 17 oncogene homolog (avian) antibody, V jun sarcoma virus 17 oncogene homolog antibody, V-jun avian sarcoma virus 17 oncogene homolog antibody, vJun Avian Sarcoma Virus 17 Oncogene Homolog antibody

UniProt: P05412

Pathways: MAPK Signaling, RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins