CDC25A antibody (Ser178)

Catalog No. ABIN7179988

The Rabbit Polyclonal anti-CDC25A antibody (ABIN7179988) specifically detects CDC25A in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for CDC25A antibody (Ser178) (ABIN7179988)

Target: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC25A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CDC25A Antibody

Binding Specificity: Ser178

Purpose: CDC25A (Ab-178) Antibody

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human CDC25A around the phosphorylation site of serine 178 (Q-N-S(p)-A-P).

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CDC25A

Target: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Alternative Name: CDC25A

Background:

Background: Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.

Galaktionov K.I.,Cell 67:1181-1194(1991).
The MGC Project Team,Genome Res. 14:2121-2127(2004).
Wegener S., Eur. J. Cell Biol. 79:810-815(2000).

Aliases: Cdc 25a antibody, CDC25A antibody, CDC25A2 antibody, CDC25A2 CAG isoform antibody, Cell division cycle 25 homolog A (S. pombe) antibody, Cell division cycle 25A antibody, Cell division cycle 25A isoform a antibody, Cell division cycle 25A isoform b antibody, D9Ertd393e antibody, Dual specificity phosphatase Cdc25A antibody, M phase inducer phosphatase 1 antibody, M-phase inducer phosphatase 1 antibody, MGC115549 antibody, MPIP1_HUMAN antibody

UniProt: P30304

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase