IL2 Receptor beta antibody (Tyr364)

Catalog No. ABIN7180029

The Rabbit Polyclonal anti-IL2 Receptor beta antibody has been validated for WB, ELISA, IHC and IF. It is suitable to detect IL2 Receptor beta in samples from Human.

Quick Overview for IL2 Receptor beta antibody (Tyr364) (ABIN7180029)

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL2 Receptor beta antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-IL2 Receptor beta Antibody

Binding Specificity: Tyr364

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human IL-2Rbeta/CD122 around the phosphorylation site of tyrosine 364 (Q-G-Y(p)-F-F).

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:200, IF:1:100-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IL2 Receptor beta

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Alternative Name: IL2RB

Background:

Background: Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.

Hatakeyama M., Science 244:551-556(1989).
Dunham I., Nature 402:489-495(1999).
Mulloy J.C., J. Virol. 70:3599-3605(1996)

Aliases: CD122 antibody, CD122 antigen antibody, High affinity IL 2 receptor beta subunit antibody, High affinity IL 2 receptor subunit beta antibody, High affinity IL-2 receptor subunit beta antibody, IL-2 receptor subunit beta antibody, IL-2R subunit beta antibody, IL-2RB antibody, IL15RB antibody, IL2 receptor antibody, IL2RB antibody, IL2RB_HUMAN antibody, Interleukin 2 receptor beta antibody, Interleukin-2 receptor subunit beta antibody, P70 75 antibody, P70-75 antibody, P7075 antibody, p75 antibody

UniProt: P14784

Pathways: JAK-STAT Signaling, Growth Factor Binding