CAMKII gamma antibody (C-Term)

Catalog No. ABIN7180135

The Rabbit Polyclonal anti-CAMKII gamma antibody (ABIN7180135) specifically detects CAMKII gamma in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for CAMKII gamma antibody (C-Term) (ABIN7180135)

Target: CAMKII gamma (CAMK2G) (Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAMKII gamma antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CAMKII gamma Antibody

Binding Specificity: C-Term

Purpose: CAMK2G/CAMK2B Antibody

Cross-Reactivity: Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human CaMK2beta/γ,.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CAMKII gamma

Target: CAMKII gamma (CAMK2G) (Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G))

Alternative Name: CAMK2G

Background:

Background: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.Deloukas P., Nature 429:375-381(2004).Breen M.A., Biochem. Biophys. Res. Commun. 236:473-478(1997).Tombes R.M., Biochim. Biophys. Acta 1355:281-292(1997).

Aliases: Calcium/calmodulin-dependent protein kinase type II gamma chain, EC 2.7.11.17, CaM-kinase II gamma chain, CaM kinase II subunit gamma, CaMK-II subunit gamma

UniProt: Q13555, Q13554

Pathways: WNT Signaling, Interferon-gamma Pathway, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of long-term Neuronal Synaptic Plasticity