CYP21A2 antibody (C-Term)

Catalog No. ABIN7180149

The Rabbit Polyclonal anti-CYP21A2 antibody is suitable to detect CYP21A2 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for CYP21A2 antibody (C-Term) (ABIN7180149)

Target: CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP21A2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CYP21A2 Antibody

Binding Specificity: C-Term

Purpose: CYP21A2 Antibody

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human CYP21A2.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CYP21A2

Target: CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))

Alternative Name: CYP21A2

Background:

Background: Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids.

Higashi Y., Proc. Natl. Acad. Sci. U.S.A. 83:2841-2845(1986).
White P.C., Proc. Natl. Acad. Sci. U.S.A. 83:5111-5115(1986).
Rodrigues N.R., EMBO J. 6:1653-1661(1987).

Aliases: CYP21 antibody, 21 OHase antibody, 21-OHase antibody, CA21H antibody, CAH1 antibody, CP21A_HUMAN antibody, CPS1 antibody, CYP21A 2 antibody, CYP21A2 antibody, CYP21B antibody, Cytochrome P-450c21 antibody, Cytochrome P450 21 antibody, Cytochrome P450 C21B antibody, Cytochrome P450 XXI antibody, Cytochrome P450, family 21, subfamily A, polypeptide 2 antibody, Cytochrome P450, subfamily XXIA (steroid 21 hydroxylase, congenital adrenal hyperplasia), polypeptide 2 antibody, Cytochrome P450-C21 antibody, Cytochrome P450-C21B antibody, P450 C21 antibody, P450 C21B antibody, P450c21B antibody, Steroid 21 hydroxylase antibody, Steroid 21 monooxygenase antibody, Steroid 21-hydroxylase antibody

UniProt: P08686

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process