Laminin beta 1 antibody (C-Term)

Catalog No. ABIN7180195

This anti-Laminin beta 1 antibody is a Rabbit Polyclonal antibody detecting Laminin beta 1 in WB, IHC, ELISA and IF. Suitable for Human.

Quick Overview for Laminin beta 1 antibody (C-Term) (ABIN7180195)

Target: Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Laminin beta 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Laminin beta 1 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human LAMB1.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Laminin beta 1

Target: Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))

Alternative Name: LAMB1

Background:

Background: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface.

Vuolteenaho R., J. Biol. Chem. 265:15611-15616(1990).
Pikkarainen T., J. Biol. Chem. 262:10454-10462(1987).
Scherer S.W., Science 300:767-772(2003).

Aliases: CLM antibody, Cutis laxa with marfanoid phenotype antibody, LAM B1 antibody, LAMB 1 antibody, LAMB1 antibody, LAMB1_HUMAN antibody, Laminin B1 antibody, Laminin B1 chain antibody, Laminin beta 1 chain antibody, Laminin beta 1 chain precursor antibody, Laminin beta1 antibody, Laminin subunit beta 1 antibody, Laminin subunit beta-1 antibody, Laminin-1 subunit beta antibody, Laminin-10 subunit beta antibody, Laminin-12 subunit beta antibody, Laminin-2 subunit beta antibody, Laminin-6 subunit beta antibody, Laminin-8 subunit beta antibody, LIS5 antibody, MGC142015 antibody

UniProt: P07942