NUB1 antibody (C-Term)

Catalog No. ABIN7180218

The Rabbit Polyclonal anti-NUB1 antibody has been validated for WB, IHC and ELISA. It is suitable to detect NUB1 in samples from Human.

Quick Overview for NUB1 antibody (C-Term) (ABIN7180218)

Target: NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-NUB1 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human NYREN18.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NUB1

Target: NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))

Alternative Name: NUB1

Background:

Background: Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2.

Sarah M. Mense, Toxicol. Sci., Sep 2006, 93: 125 - 135.
Gunter Schmidtke, J. Biol. Chem., Jul 2006, 281: 20045 - 20054.s
Kunikazu Tanji, Am. J. Pathol., Aug 2006, 169: 553 - 565.
Miguel Ramalho-Santos, Science, Oct 2002, 298: 597.

Aliases: BS4 antibody, NEDD8 µLtimate buster 1 antibody, Negative regulator of ubiquitin like proteins 1 antibody, Negative regulator of ubiquitin-like proteins 1 antibody, NUB1 antibody, NUB1_HUMAN antibody, NUB1L antibody, NY REN 18 antibody, NYREN18 antibody, Renal carcinoma antigen NY-REN-18 antibody

UniProt: Q9Y5A7