Thrombomodulin antibody (C-Term)

Catalog No. ABIN7180265

This Rabbit Polyclonal antibody specifically detects Thrombomodulin in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Thrombomodulin antibody (C-Term) (ABIN7180265)

Target: Thrombomodulin (THBD)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Thrombomodulin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Thrombomodulin Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human THBD.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Thrombomodulin

Target: Thrombomodulin (THBD)

Alternative Name: THBD

Background:

Background: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Suzuki K., EMBO J. 6:1891-1897(1987).
Wen D., Biochemistry 26:4350-4357(1987). Jackman R.W., Proc. Natl. Acad. Sci. U.S.A. 84:6425-6429(1987).

Aliases: AHUS 6 antibody, AHUS6 antibody, BDCA 3 antibody, BDCA3 antibody, CD 141 antibody, CD141 antibody, CD141 antigen antibody, Fetomodulin antibody, Thbd antibody, THPH12 antibody, THRM antibody, Thrombomodulin antibody, TM antibody, TRBM_HUMAN antibody

UniProt: P07204