KRT14 antibody

Catalog No. ABIN7180977

The Mouse Monoclonal anti-KRT14 antibody has been validated for IHC and ELISA. It is suitable to detect KRT14 in samples from Human.

Quick Overview for KRT14 antibody (ABIN7180977)

Target: KRT14 (Keratin 14 (KRT14))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT14 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-KRT14 Antibody

Purpose: KRT14/KRT16/KRT5/KRT6A/KRT8 Monoclonal Antibody

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human Cytokeratin Pan

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KRT14

Target: KRT14 (Keratin 14 (KRT14))

Alternative Name: KRT14

Background:

Background: Cytokeratin pan is part of a subfamily of intermediate filament proteins that are characterized by remarkable biochemical diversity, and represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight between 40 kDa- 68 kDa, and an isoelectric pH between 4.9-7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. The composition of cytokeratin pairs vary with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

Aliases: CARD2, CK-4, CK-6C, CK-6E, CK-8, CK14, CK16, CK4, CK5, CK6A, CK6C, CK6D, CK8, CYK4, CYK8, DDD, DDD1, EBS2, EBS3, EBS4, FNEPPK, K14, K16, K1CP, K2C8, K4, K5, K6A, K6C, K6D, K8, KO, KRT14, KRT16, KRT16A, KRT5, KRT5A, KRT6A, KRT6C, KRT6D, KRT8, NEPPK, NFJ, PC1, PC3, WSN1, 58 kDa cytokeratin, CK-14, CK-16, CK-5, CK-6A, CK-6D, CK-8, cytokeratin 14, cytokeratin 16, cytokeratin 4, cytokeratin 6A, cytokeratin 6C, cytokeratin 6D, Cytokeratin-14, Cytokeratin-16, Cytokeratin-5, Cytokeratin-6A, cytokeratin-6C, Cytokeratin-6D, cytokeratin-6E, Cytokeratin-8, epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types, focal non-epidermolytic palmoplantar keratoderma, Hom s 5, K14, K16, K5, K6A, K8, kamp-keratin derived antimicrobial peptide, KDAMP, keratin 14, type I, keratin 16, type I, keratin 4, type II, keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types), keratin 5, type II, keratin 6A, , type II, keratin 6A, type II, keratin 8, type II, keratin K6h, keratin, epidermal type II, K6A, Keratin, type I cytoskeletal 14, Keratin, type I cytoskeletal 16, Keratin, type II cytoskeletal 5, Keratin, type II cytoskeletal 6A, Keratin, type II cytoskeletal 8, Keratin-14, Keratin-16, Keratin-5, Keratin-6A, keratin-6C, Keratin-8, pankeratin, type-II keratin Kb12, type-II keratin Kb4, Type-II keratin Kb5, Type-II keratin Kb6, Type-II keratin Kb8

UniProt: P02533, P08779, P13647, P02538, P05787