H2AFZ antibody (AA 2-14)

Catalog No. ABIN7181496

Product Details anti-H2AFZ Antibody

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Binding Specificity: AA 2-14

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2AFZ antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Synthesized peptide derived from Human Histone H2A.Z protein (2-14aa)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: ICC:1:10-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for H2AFZ

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Alternative Name: H2AFZ (H2AFZ Products)

Background:

Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.

Aliases: Histone H2A.Z (H2A/z), H2AFZ, H2AZ

UniProt: P0C0S5

Pathways: Telomere Maintenance