REV3L antibody

Catalog No. ABIN7183460

This Rabbit Polyclonal antibody specifically detects REV3L in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for REV3L antibody (ABIN7183460)

Target: REV3L (REV3-Like, Polymerase (DNA Directed), Zeta, Catalytic Subunit (REV3L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REV3L antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-REV3L Antibody

Purpose: REV3L Antibody

Cross-Reactivity: Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human DNA Polymerase ζ,.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for REV3L

Target: REV3L (REV3-Like, Polymerase (DNA Directed), Zeta, Catalytic Subunit (REV3L))

Alternative Name: REV3L

Background:

Background: Interacts with MAD2L2 to form the error prone DNA polymerase zeta involved in translesion DNA synthesis.

Gibbs P.E.M., Proc. Natl. Acad. Sci. U.S.A. 95:6876-6880(1998).
Lin W., Mutat. Res. 433:89-98(1999).
Morelli C., Cytogenet. Cell Genet. 83:18-20(1998).

Aliases: REV3L antibody, POLZ antibody, REV3 antibody, DNA polymerase zeta catalytic subunit antibody, EC 2.7.7.7 antibody, Protein reversionless 3-like antibody, REV3-like antibody, hREV3 antibody

UniProt: O60673

Pathways: DNA Damage Repair