HEY2 antibody

Catalog No. ABIN7183626

The Rabbit Polyclonal anti-HEY2 antibody is suitable to detect HEY2 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for HEY2 antibody (ABIN7183626)

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEY2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HEY2 Antibody

Purpose: HEY2 Antibody

Cross-Reactivity: Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human HEY2.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HEY2

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Alternative Name: HEY2

Background:

Background: Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.

Chin M.T., J. Biol. Chem. 275:6381-6387(2000).
Nakagawa O., Proc. Natl. Acad. Sci. U.S.A. 97:13655-13660(2000).
Iso T., Mol. Cell. Biol. 21:6071-6079(2001).

Aliases: bHLHb32 antibody, Cardiovascular helix loop helix factor 1 antibody, Cardiovascular helix-loop-helix factor 1 antibody, CHF1 antibody, Class B basic helix-loop-helix protein 32 antibody, GRIDLOCK antibody, GRL antibody, Hairy and enhancer of split related 2 antibody, Hairy and enhancer of split-related protein 2 antibody, Hairy related transcription factor 2 antibody, Hairy-related transcription factor 2 antibody, Hairy/enhancer-of-split related with YRPW motif protein 2 antibody, hCHF1 antibody, HERP antibody, HERP1 antibody, HES related repressor protein 1 antibody, HES-related repressor protein 2 antibody, HESR-2 antibody, HESR2 antibody, hey2 antibody, HEY2_HUMAN antibody, hHRT2 antibody, HRT-2 antibody, HRT2 antibody, MGC10720 antibody, Protein gridlock homolog antibody

UniProt: Q9UBP5

Pathways: Regulation of Muscle Cell Differentiation