HEY2 antibody (AA 40-120)

Catalog No. ABIN7220728

This Rabbit Polyclonal antibody specifically detects HEY2 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for HEY2 antibody (AA 40-120) (ABIN7220728)

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEY2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-HEY2 Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-HRT2 Polyclonal Antibody

Specificity: HRT2 Polyclonal Antibody detects endogenous levels of HRT2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human HRT2 at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HEY2

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Alternative Name: HRT2

Background: HEY2, BHLHB32, CHF1, GRL, HERP, HERP1, HRT2, Hairy/enhancer-of-split related with YRPW motif protein 2, Cardiovascular helix-loop-helix factor 1, hCHF1, Class B basic helix-loop-helix protein 32, bHLHb32, HES-related repressor protein 2, HaHEY2 encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The hes related family bHLH transcription factor with YRPW motif 2 forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.

Molecular Weight: 36kD

Gene ID: 23493

UniProt: Q9UBP5

Pathways: Regulation of Muscle Cell Differentiation