OAT antibody
Quick Overview for OAT antibody (ABIN7183931)
Target
See all OAT AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Mouse, Rat
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from Internal of Human OAT.
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Isotype
- IgG
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Application Notes
- WB:1:500-1:3000,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- OAT (Ornithine Aminotransferase (OAT))
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Alternative Name
- OAT
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Background
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Background: This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.
ana G., Proc. Natl. Acad. Sci. U.S.A. 83:1203-1207(1986).
Ramesh V., DNA 5:493-501(1986).Aliases: OAT antibody, Ornithine aminotransferase antibody, mitochondrial antibody, EC 2.6.1.13 antibody, Ornithine delta-aminotransferase antibody, Ornithine--oxo-acid aminotransferase) [Cleaved into: Ornithine aminotransferase antibody, hepatic form, Ornithine aminotransferase antibody, renal form] antibody
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UniProt
- P04181
Target
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