DCK antibody (AA 181-260)

Catalog No. ABIN714176

The Rabbit Polyclonal anti-DCK antibody is suitable to detect DCK in samples from Human. It has been validated for IHC (p), IF (cc), IF (p) and IHC (fro).

Quick Overview for DCK antibody (AA 181-260) (ABIN714176)

Target: DCK (Deoxycytidine Kinase (DCK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCK antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-DCK Antibody

Binding Specificity: AA 181-260

Purpose: DCK Polyclonal Antibody

Predicted Reactivity: Human,Mouse,Rat,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DCK

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DCK

Target: DCK (Deoxycytidine Kinase (DCK))

Alternative Name: DCK

Background:

Synonyms: DCK, dCK, DCK protein, DCK_HUMAN, Deoxycytidine kinase, EC 2.7.1, EC 2.7.1.74, MGC117410, MGC138632, OTTHUMP00000219118, OTTHUMP00000219119.

Background: Deoxycytidine kinase is responsible for the phosphorylation of several deoxyribonucleosides and their analogs. Deficiency of this enzyme activity is associated with resistance to antiviral and anticancer chemotherapeutic agents, whereas increased enzyme activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. It is the rate limiting enzyme in the activation of many important anticancer and retroviral drugs and its activity is often decreased in cells that are resistant to cytosine arabinoside.

Gene ID: 1633