TP53INP2 antibody

Catalog No. ABIN7184287

Product Details anti-TP53INP2 Antibody

Target: TP53INP2 (Tumor Protein P53 Inducible Nuclear Protein 2 (TP53INP2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TP53INP2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human TP53INP2.

Isotype: IgG

Application Details

Application Notes: IHC:1:50-1:100, IF:1:100-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TP53INP2

Target: TP53INP2 (Tumor Protein P53 Inducible Nuclear Protein 2 (TP53INP2))

Alternative Name: Tp53inp2 (TP53INP2 Products)

Synonyms: 1110029F20Rik antibody, Tp53inp2 antibody, C20orf110 antibody, DOR antibody, PINH antibody, dJ1181N3.1 antibody, Trp53inp2 antibody, tumor protein p53 inducible nuclear protein 2 antibody, transformation related protein 53 inducible nuclear protein 2 antibody, TP53INP2 antibody, Trp53inp2 antibody, Tp53inp2 antibody

Background:

Background: Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.

Baumgartner B.G., Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
Deloukas P., Nature 414:865-871(2001).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

Aliases: Tp53inp2 antibody, Dor antibody, Trp53inp2 antibody, Tumor protein p53-inducible nuclear protein 2 antibody, Diabetes and obesity-regulated protein antibody

UniProt: Q8CFU8