ZFHX3 antibody

Catalog No. ABIN7184359

This anti-ZFHX3 antibody is a Rabbit Polyclonal antibody detecting ZFHX3 in ELISA and IHC. Suitable for Human.

Quick Overview for ZFHX3 antibody (ABIN7184359)

Target: ZFHX3 (Zinc Finger Homeobox 3 (ZFHX3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFHX3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-ZFHX3 Antibody

Purpose: ZFHX3 Antibody

Cross-Reactivity: Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human ZFHX3.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ZFHX3

Target: ZFHX3 (Zinc Finger Homeobox 3 (ZFHX3))

Alternative Name: ZFHX3

Background:

Background: Transcriptional repressor. It inhibits the enhancer element of the AFP gene by binding to its AT-rich core sequence. Regulator of myoblasts differentiation through the binding to the AT-rich sequence of MYF6 promoter and promoter repression. Down-regulates the MUC5AC promoter in gastric cancer.

Miura Y., J. Biol. Chem. 270:26840-26848(1995).
Morinaga T., Mol. Cell. Biol. 11:6041-6049(1991).
Martin J., Nature 432:988-994(2004).

Aliases: ZFHX3 antibody, ATBF1Zinc finger homeobox protein 3 antibody, AT motif-binding factor 1 antibody, AT-binding transcription factor 1 antibody, Alpha-fetoprotein enhancer-binding protein antibody, Zinc finger homeodomain protein 3 antibody, ZFH-3 antibody

UniProt: Q15911

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development