ACTN2 antibody (N-Term)

Catalog No. ABIN7184407

This anti-ACTN2 antibody is a Rabbit Polyclonal antibody detecting ACTN2 in WB, IHC, ELISA and IF. Suitable for Human.

Quick Overview for ACTN2 antibody (N-Term) (ABIN7184407)

Target: ACTN2 (Actinin, alpha 2 (ACTN2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACTN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-ACTN2 Antibody

Binding Specificity: N-Term

Purpose: ACTN2/ACTN3 Antibody

Cross-Reactivity: Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human Actin alpha-2/3.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ACTN2

Target: ACTN2 (Actinin, alpha 2 (ACTN2))

Alternative Name: ACTN2

Background:

Background: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.Beggs A.H., J. Biol. Chem. 267:9281-9288(1992).Tiso N., Biochem. Biophys. Res. Commun. 265:256-259(1999).Faulkner G., J. Cell Biol. 146:465-475(1999).

Aliases: Alpha-actinin-2, Alpha-actinin skeletal muscle isoform 2, F-actin cross-linking protein, ACTN2,

UniProt: P35609, Q08043

Pathways: Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity