AZI2 antibody (N-Term)

Catalog No. ABIN7184418

The Rabbit Polyclonal anti-AZI2 antibody has been validated for ELISA and WB. It is suitable to detect AZI2 in samples from Human.

Quick Overview for AZI2 antibody (N-Term) (ABIN7184418)

Target: AZI2 (5-Azacytidine Induced 2 (AZI2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AZI2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-AZI2 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human, Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human AZI2.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for AZI2

Target: AZI2 (5-Azacytidine Induced 2 (AZI2))

Alternative Name: AZI2

Background:

Background: Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.

Fujita F., Mol. Cell. Biol. 23:7780-7793(2003).
Ota T., Nat. Genet. 36:40-45(2004).
Sasai M., J. Immunol. 174:27-30(2005).

Aliases: 5 azacytidine induced protein 2 antibody, 5-azacytidine-induced protein 2 antibody, AA410145 antibody, AZ2 antibody, AZI2 antibody, AZI2_HUMAN antibody, MGC112644 antibody, Nak associated protein 1 antibody, Nak-associated protein 1 antibody, NAP1 antibody, NF kappa B activating kinase associated protein 1 antibody, NF-kappa-B-activating kinase-associated protein 1 antibody, TILP antibody, TILP(S) antibody

UniProt: Q9H6S1