Acrosin antibody
Quick Overview for Acrosin antibody (ABIN7189634)
Target
See all Acrosin (ACR) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- ACR Antibody
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Purification
- Antigen affinity purification
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Immunogen
- Synthetic peptide of Human ACR
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Acrosin (ACR)
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Alternative Name
- ACR
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Background
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Background: Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.
Aliases: Acr antibody, ACRO_HUMAN antibody, Acrosin heavy chain antibody, Acrosin precursor antibody, ACRS antibody, Preproacrosin antibody, Proacrosin antibody
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UniProt
- P10323
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Pathways
- cAMP Metabolic Process
Target
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