Claudin 11 antibody

Catalog No. ABIN7190272

This Rabbit Polyclonal antibody specifically detects Claudin 11 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for Claudin 11 antibody (ABIN7190272)

Target: Claudin 11 (CLDN11)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 11 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-Claudin 11 Antibody

Purpose: CLDN11 Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human CLDN11

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Claudin 11

Target: Claudin 11 (CLDN11)

Alternative Name: CLDN11

Background:

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis.

Aliases: Claudin 11 antibody, Claudin-11 antibody, CLD11_HUMAN antibody, Cldn11 antibody, Oligodendrocyte transmembrane protein antibody, Oligodendrocyte-specific protein antibody, OSP antibody, OTM antibody

UniProt: O75508

Pathways: Hepatitis C