EID3 antibody

Catalog No. ABIN7190538

The Rabbit Polyclonal anti-EID3 antibody (ABIN7190538) specifically detects EID3 in ELISA, IHC and WB. The antibody is reactive with Human samples.

Quick Overview for EID3 antibody (ABIN7190538)

Target: EID3 (EP300 Interacting Inhibitor of Differentiation 3 (EID3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EID3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-EID3 Antibody

Purpose: EID3 Antibody

Cross-Reactivity: Mouse

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human EID3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for EID3

Target: EID3 (EP300 Interacting Inhibitor of Differentiation 3 (EID3))

Alternative Name: EID3

Background:

Background: EID3 is highly expressed in testis and shows homology to a region of EID1 implicated in binding to CBP/p300. EID3 acts as a potent inhibitor of nuclear receptor transcriptional activity by a mechanism that is independent of direct interactions with nuclear receptors, including SHP. Furthermore, EID3 directly binds to and blocks the SRC-1 interacting domain of CBP, which has been implicated to act as the interaction surface for nuclear receptor co-activators. Consistent with this idea, EID3 prevents recruitment of CBP to a natural nuclear receptor-regulated promoter.

Aliases: E1A-like inhibitor of differentiation 3 antibody, EID 3 antibody, EID-1-like inhibitor of differentiation 3 antibody, EID-3 antibody, EID3 antibody, EID3_HUMAN antibody, EP300 interacting inhibitor of differentiation 3 antibody, EP300-interacting inhibitor of differentiation 3 antibody, FLJ25832 antibody, Non-SMC element 4, S. cerevisiae, homolog of, B antibody, Non-structural maintenance of chromosomes element 4 homolog B antibody, NSE4B antibody, NSMCE4B antibody

UniProt: Q8N140