SH2B2 antibody

Catalog No. ABIN7192349

The Rabbit Polyclonal anti-SH2B2 antibody is suitable to detect SH2B2 in samples from Human. It has been validated for ELISA and IHC.

Quick Overview for SH2B2 antibody (ABIN7192349)

Target: SH2B2 (SH2B Adaptor Protein 2 (SH2B2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH2B2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-SH2B2 Antibody

Purpose: SH2B2 Antibody

Cross-Reactivity: Rat

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human SH2B2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SH2B2

Target: SH2B2 (SH2B Adaptor Protein 2 (SH2B2))

Alternative Name: SH2B2

Background:

Background: The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.

Aliases: SH2B2 antibody, APS antibody, SH2B adapter protein 2 antibody, Adapter protein with pleckstrin homology and Src homology 2 domains antibody, SH2 and PH domain-containing adapter protein APS antibody

UniProt: O14492

Pathways: Carbohydrate Homeostasis, Brown Fat Cell Differentiation