SPRN antibody

Catalog No. ABIN7192636

This Rabbit Polyclonal antibody specifically detects SPRN in IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for SPRN antibody (ABIN7192636)

Target: SPRN (Shadow of Prion Protein (SPRN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPRN antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-SPRN Antibody

Purpose: SPRN Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human SPRN

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SPRN

Target: SPRN (Shadow of Prion Protein (SPRN))

Alternative Name: SPRN

Background:

Background: SPRN (shadow of prion protein), also known as SHO or SHADOO, is a 151 amino acid cytoplasmic protein that is mainly expressed in brain. SPRN is considered a prion-like protein that has PrP(C)-like neuroprotective activity and may act as a modulator for the biological actions of normal and abnormal PrP. In humans, mutations in the gene encoding SPRN may be associated with variant and sporadic Creutzfeldt-Jakob disease, a degenerative neurological disorder that is incurable and invariably fatal.

Aliases: SPRN antibody, SHO antibody, Shadow of prion protein antibody, Protein shadoo antibody

UniProt: Q5BIV9