ELMO1 antibody (AA 581-680) (Cy5)

Catalog No. ABIN715050

Product Details anti-ELMO1 Antibody (Cy5)

Target: ELMO1 (Engulfment and Cell Motility 1 (ELMO1))

Binding Specificity: AA 581-680

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELMO1 antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ELMO.

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ELMO1

Target: ELMO1 (Engulfment and Cell Motility 1 (ELMO1))

Alternative Name: ELMO1 (ELMO1 Products)

Synonyms: MGC68475 antibody, ELMO1 antibody, CED-12 antibody, CED12 antibody, ELMO-1 antibody, 6330578D22Rik antibody, C230095H21Rik antibody, ELMO1s antibody, im:7151147 antibody, wu:fq24e08 antibody, zgc:85612 antibody, engulfment and cell motility 1 antibody, engulfment and cell motility 1 S homeolog antibody, engulfment and cell motility 1 (ced-12 homolog, C. elegans) antibody, ELMO1 antibody, elmo1.S antibody, elmo1 antibody, Elmo1 antibody

Background:

Synonyms: CED 12, Ced 12 homolog 1, Ced 12 homolog, CED12, Ced12 homolog 1, Ced12 homolog, ELMO 1, Engulfment and cell motility 1, Engulfment and cell motility protein 1, KIAA0281, ELMO1_HUMAN.

Background: ELMO1 is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. ELMO1 acts in association with DOCK1 and CRK and was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. It is belived to enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

Gene ID: 9844