ATG4A antibody (AA 258-398)

Catalog No. ABIN7193210

The Mouse Monoclonal anti-ATG4A antibody has been validated for ELISA, FACS and ICC. It is suitable to detect ATG4A in samples from Human.

Quick Overview for ATG4A antibody (AA 258-398) (ABIN7193210)

Target: ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATG4A antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 8C9C2

Product Details anti-ATG4A Antibody

Binding Specificity: AA 258-398

Purpose: ATG4A Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human ATG4A (AA: 258-398) expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/100 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for ATG4A

Target: ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Alternative Name: ATG4A

Background:

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases.

Molecular Weight: 45.4 kDa

UniProt: Q8WYN0

Pathways: Autophagy