PTPRJ antibody (AA 36-210)
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- Target See all PTPRJ Antibodies
- PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
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Binding Specificity
- AA 36-210
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PTPRJ antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human CD148 (AA: extra 36-210) expressed in E. coli.
- Clone
- 6F2E12
- Isotype
- IgG1
- Top Product
- Discover our top product PTPRJ Primary Antibody
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A
- Restrictions
- For Research Use only
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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- Target
- PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
- Alternative Name
- CD148 (PTPRJ Products)
- Synonyms
- HAAP antibody, CD148 antibody, DEP1 antibody, HPTPeta antibody, R-PTP-ETA antibody, SCC1 antibody, AI450271 antibody, BET antibody, Byp antibody, DEP-1 antibody, PTPbeta2 antibody, Ptpb2 antibody, RPTPJ antibody, Scc-1 antibody, Scc1 antibody, PTPRJ antibody, acid phosphatase 1 antibody, protein tyrosine phosphatase, receptor type J antibody, protein tyrosine phosphatase, receptor type, J antibody, ACP1 antibody, PTPRJ antibody, Ptprj antibody, EUBREC_2762 antibody
- Background
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Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene.
Aliases: PTPRJ, DEP1, SCC1, HPTPeta, R-PTP-ETA
- Molecular Weight
- 146 kDa
- Gene ID
- 5795
- Pathways
- EGFR Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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