Thrombomodulin antibody (AA 297-505)

Catalog No. ABIN7193269

This Mouse Monoclonal antibody specifically detects Thrombomodulin in ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for Thrombomodulin antibody (AA 297-505) (ABIN7193269)

Target: Thrombomodulin (THBD)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Thrombomodulin antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 2C6C3

Product Details anti-Thrombomodulin Antibody

Binding Specificity: AA 297-505

Purpose: CD141 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD141 (AA: 297-505) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for Thrombomodulin

Target: Thrombomodulin (THBD)

Alternative Name: CD141

Background:

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.

Molecular Weight: 60.3 kDa

UniProt: P07204