CD177 antibody (AA 22-161)

Catalog No. ABIN7193297

The Mouse Monoclonal anti-CD177 antibody has been validated for WB, FACS and ELISA. It is suitable to detect CD177 in samples from Human.

Quick Overview for CD177 antibody (AA 22-161) (ABIN7193297)

Target: CD177 (CD177 Molecule (CD177))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD177 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Clone: 2F2C1

Product Details anti-CD177 Antibody

Binding Specificity: AA 22-161

Purpose: CD177 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD177 (AA: 22-161) expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CD177

Target: CD177 (CD177 Molecule (CD177))

Alternative Name: CD177

Background:

This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.

Molecular Weight: 46.4 kDa

Gene ID: 57126

UniProt: Q8N6Q3