IL17RA antibody (AA 33-320)

Catalog No. ABIN7193333

The Mouse Monoclonal anti-IL17RA antibody has been validated for ELISA and FACS. It is suitable to detect IL17RA in samples from Human.

Quick Overview for IL17RA antibody (AA 33-320) (ABIN7193333)

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL17RA antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 6H1B1

Product Details anti-IL17RA Antibody

Binding Specificity: AA 33-320

Purpose: CD217 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD217 (AA: 33-320) expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for IL17RA

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Alternative Name: CD217

Background:

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 96.1 kDa

Gene ID: 23765

UniProt: Q96F46

Pathways: SARS-CoV-2 Protein Interactome