MLL3 antibody (AA 1-205)

Catalog No. ABIN7193377

This Mouse Monoclonal antibody specifically detects MLL3 in ELISA, FACS, ICC and IHC. It exhibits reactivity toward Human.

Quick Overview for MLL3 antibody (AA 1-205) (ABIN7193377)

Target: MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MLL3 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC)

Clone: 6D1B9

Product Details anti-MLL3 Antibody

Binding Specificity: AA 1-205

Purpose: KMT2C Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human KMT2C (AA: 1-205) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for MLL3

Target: MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))

Alternative Name: KMT2C

Background:

This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein with an AT hook DNA-binding domain, a DHHC-type zinc finger, six PHD-type zinc fingers, a SET domain, a post-SET domain and a RING-type zinc finger. This protein is a member of the ASC-2/NCOA6 complex (ASCOM), which possesses histone methylation activity and is involved in transcriptional coactivation. [provided by RefSeq, Jul 2008]

Molecular Weight: 541.4 kDa

UniProt: Q8NEZ4

Pathways: Warburg Effect